Gen // CTX
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GenCTX

Life evolves. Cells decide. We program that decision.

SECTION 01 / INTRO
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10,000,000
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Lives lost to cancer every year — World Health Organization, 2024

Cancer by the Numbers

1 in 3
People will be diagnosed with cancer at some point in their lifetime Source: American Cancer Society
20M+
New cancer cases diagnosed globally every year, with incidence rising as populations age Source: World Health Organization
~90%
Of cancer deaths are driven by metastasis, recurrence, or therapy resistance Source: Nature Reviews Cancer
$400B+
Global spending on oncology medicines annually, with sustained double-digit growth Source: IQVIA Global Oncology Trends
SECTION 02 / PLATFORM
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Sense. Decide. Act.

Our platform turns the flexibility of cancer—its genomic instability—into an exploitable weakness.

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01

Sense

Reading key molecular cues

Cells run internal programs that govern growth, stress response, and repair. Our constructs tap into these existing signals—reading the molecular language life already speaks.

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02

Decide

Interpreting cellular context

Disease emerges when cellular programs fail or are overwritten. Our logic layer interprets internal state and determines the right response—something evolution left unfinished.

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03

Act

Restoring cellular control

Our constructs transform cells from passive victims of disease into active decision-makers—activating therapeutic responses when needed and shutting off when balance is restored.

LEARN MORE

Explore the full technical platform

Read More →

Backed By

SECTION 03 / PEOPLE
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Leadership

The minds building
the future of medicine.

Dylan Paoletti

Dylan Paoletti

Co-Founder & CEO

Biotech innovator with a background in SynBio and scientific presentation.

Leads product vision, R&D, and company strategy.

Dr. Peter Evans

Dr. Peter Evans

Co-Founder & COO

Ex-FDA scientist with expertise in molecular biology and public health.

Oversees science, finances, and planning.

Dr. Yildirim Dogan

Dr. Yildirim Dogan

Head of R&D

Ex-Director at Moderna and AVROBIO.

Cancer research and gene therapy development and clinical translation expertise.

Dr. Chris Mason

Dr. Chris Mason, MD, PhD

Senior Advisor

Renowned gene therapy expert and advisor to 11+ biotech startups.

Focused on long-term strategy and clinical commercialization.

SECTION 04 / WHY GENCTX
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Gen CTX
[ˈjen-ˌsi-tē-eks]
The Name

Genetic Circuit Therapeutics

Most diseases emerge when biological systems make the wrong decisions at the wrong time. Cells operate through logic, feedback, and state. When that control fails, pathology follows.

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GenCTX intervenes at the level of decision-making.